BDBM114904 7-keto-N-(p-tolyl)-5,6-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::MLS000681581::N-(4-methylphenyl)-7-oxidanylidene-5,6-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::N-(4-methylphenyl)-7-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::N-(4-methylphenyl)-7-oxo-5,6-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::SMR000312258::cid_5294610

SMILES COc1c(Nc2cc(NC(=O)C3CC3)nnc2C(N)=O)cccc1-c1cc(P(=O)(C2CC2)C2CC2)n(C)n1

InChI Key InChIKey=KSYPNTQQWJUKCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 114904   

LigandChemical structure of BindingDB Monomer ID 114904BDBM114904(US20260001898, Example A1)
Affinity DataKd:  0.00400nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [583-855](Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114904BDBM114904(US20260001898, Example A1)
Affinity DataKd:  0.0200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3 [822-1111](Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114904BDBM114904(US20260001898, Example A1)
Affinity DataKd:  210nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 114904BDBM114904(US20260001898, Example A1)
Affinity DataKd:  550nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [549-809](Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114904BDBM114904(US20260001898, Example A1)
Affinity DataKd:  790nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1 [875-1153](Human)
Broad Institute

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 114904BDBM114904(US20260001898, Example A1)
Affinity DataKd:  6.90E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2026
Entry Details
US Patent