BDBM11451 4-{[5-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino}benzene-1-sulfonamide::triazolo[1,5-a]pyrimidine 13

SMILES CCN(CC)c1cc(Nc2ccc(cc2)S(N)(=O)=O)n2ncnc2n1

InChI Key InChIKey=QZYYANMOAVILCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11451   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Vernalis (R&D)

LigandPNGBDBM11451(4-{[5-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimid...)
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2006
Entry Details Article
PubMed
LigandPNGBDBM11451(4-{[5-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimid...)
Affinity DataIC50: 3.40E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Vernalis (R&D)

LigandPNGBDBM11451(4-{[5-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimid...)
Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2006
Entry Details Article
PubMed