BDBM113824 1-(2-((4-Methoxyphenyl)amino)-3-oxo-3,4 dihydroquinoxalin- 6-yl)-3-phenylurea (VIIa)

SMILES COc1ccc(Nc2nc3ccc(NC(=O)Nc4ccccc4)cc3[nH]c2=O)cc1

InChI Key InChIKey=BEIDTMNTWXSCKC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 113824   

TargetVascular endothelial growth factor receptor 2(Human)
Ain Shams University

LigandPNGBDBM113824(1-(2-((4-Methoxyphenyl)amino)-3-oxo-3,4 dihydroqui...)
Affinity DataIC50: 1.03E+4nMT: 2°CAssay Description:Assays are performed for 15 min at 30 °C, with 50 µM of P33-ATP in a final volume of 25 µL. The assays are terminated by spotting 20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2014
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Ain Shams University

LigandPNGBDBM113824(1-(2-((4-Methoxyphenyl)amino)-3-oxo-3,4 dihydroqui...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of VEGFR-2 (unknown origin) after 15 mins in presence of [33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Ain Shams University

LigandPNGBDBM113824(1-(2-((4-Methoxyphenyl)amino)-3-oxo-3,4 dihydroqui...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed