BDBM113720 US8637507, C-5

SMILES CCC1CN(C(=O)Nc2ccc(Cl)cc2F)c2ccc(cc2O1)-c1ccc(OCC(C)(C)C(O)=O)nc1

InChI Key InChIKey=ARVPCQBTINRJQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 113720   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113720(US8637507, C-5)
Affinity DataIC50: 118nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
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