BDBM11358 (2S)-N-hydroxy-2-[(4-methoxybenzene)[(2-nitrophenyl)methyl]sulfonamido]propanamide::Hydroxamate 39::N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanine hydroxamate

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1[N+]([O-])=O)[C@@H](C)C(=O)NO

InChI Key InChIKey=XVUIGVGFVWRFJO-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11358   

Target72 kDa type IV collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi:  13nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi:  19nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi:  20nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi:  24nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi:  39nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi: >200nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi: >200nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi

LigandPNGBDBM11358(N-4-Methoxyphenylsulfonyl-N-2-nitrobenzyl-L-alanin...)
Affinity DataKi: >200nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed