BDBM11290 N-(4-chloro-2-fluorophenyl)-2-{[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]sulfanyl}acetamide::acs.jmedchem.1c00409_ST.806::pyrimidine-containing compound 27

SMILES Cc1cc(nc(SCC(=O)Nc2ccc(Cl)cc2F)n1)C(F)(F)F

InChI Key InChIKey=HYEIKCOUEGKGTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11290   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11290(N-(4-chloro-2-fluorophenyl)-2-{[4-methyl-6-(triflu...)
Affinity DataIC50: 5.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11290(N-(4-chloro-2-fluorophenyl)-2-{[4-methyl-6-(triflu...)
Affinity DataIC50: 5.00E+5nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed