BDBM11282 N-(4-butyl-2-methylphenyl)-2-[(5-cyano-4-cyclohexyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetamide::acs.jmedchem.1c00409_ST.775::pyrimidinone-containing compound 19

SMILES CCCCc1ccc(NC(=O)CSc2nc(C3CCCCC3)c(C#N)c(=O)[nH]2)c(C)c1

InChI Key InChIKey=GBDKYZQJONYDPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11282   

TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11282(N-(4-butyl-2-methylphenyl)-2-[(5-cyano-4-cyclohexy...)
Affinity DataIC50: 2.00E+5nMAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
National Tsing Hua University

LigandPNGBDBM11282(N-(4-butyl-2-methylphenyl)-2-[(5-cyano-4-cyclohexy...)
Affinity DataIC50: 2.00E+5nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed