BDBM112001 US8623892, 3

SMILES CC(C)C(O)(c1cnn[nH]1)c1ccc2cc(OC(F)F)c(OC(F)F)cc2c1

InChI Key InChIKey=ZBRAJOQFSNYJMF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 112001   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

US Patent
LigandPNGBDBM112001(US8623892, 3)
Affinity DataIC50: 220nMAssay Description:In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
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TargetCytochrome P450 2C9(Human)
Viamet Pharmaceuticals

US Patent
LigandPNGBDBM112001(US8623892, 3)
Affinity DataIC50: 1.20E+4nMAssay Description:In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Viamet Pharmaceuticals

US Patent
LigandPNGBDBM112001(US8623892, 3)
Affinity DataIC50: 1.90E+4nMAssay Description:In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

US Patent
LigandPNGBDBM112001(US8623892, 3)
Affinity DataIC50: 2.30E+4nMAssay Description:In the design of clinically safe and effective metalloenzyme inhibitors, use of the most appropriate metal-binding group for the particular target an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
Go to US Patent