BDBM111336 US8614253, 28-12::US8614253, 42-2::US9241942, 42-2

SMILES COc1cc(cc(C=O)c1O)-c1cccc(c1)C(=O)NC1CCCCC1

InChI Key InChIKey=GSQHHLXIQFAXPR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 111336   

LigandPNGBDBM111336(US8614253, 42-2 | US8614253, 28-12 | US9241942, 42...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
Go to US Patent

LigandPNGBDBM111336(US8614253, 42-2 | US8614253, 28-12 | US9241942, 42...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:IRE-1 alpha, T1 RNase, and RNase A assays carried out in vitro with several o-vanillin derivatives to demonstrate selectivity of the derivatives for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2014
Entry Details
Go to US Patent

LigandPNGBDBM111336(US8614253, 42-2 | US8614253, 28-12 | US9241942, 42...)
Affinity DataIC50: 19nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM111336(US8614253, 42-2 | US8614253, 28-12 | US9241942, 42...)
Affinity DataIC50: 19nMpH: 7.5Assay Description:A fusion protein comprising glutathione S transferase (GST) and human IRE-1α (GST-IRE-1α) was obtained from a 500 ml baculovirus-infected i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2016
Entry Details
Go to US Patent