BDBM11103 2-cyanopyrrolidine 21aj::5-chloro-6-{[(2R,5S)-5-{[(2S)-2-cyanopyrrolidin-1-yl]carbonyl}pyrrolidin-2-yl]methoxy}pyridine-3-carboxylic acid

SMILES OC(=O)c1cnc(OC[C@H]2CC[C@H](N2)C(=O)N2CCC[C@H]2C#N)c(Cl)c1

InChI Key InChIKey=ULLYVWJUMAKNAI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11103   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM11103(5-chloro-6-{[(2R,5S)-5-{[(2S)-2-cyanopyrrolidin-1-...)
Affinity DataKi:  0.450nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed