BDBM11089 2-cyanopyrrolidine 21m::5-chloro-2-{[(2R,5S)-5-{[(2S)-2-cyanopyrrolidin-1-yl]carbonyl}pyrrolidin-2-yl]methoxy}benzoic acid

SMILES OC(=O)c1cc(Cl)ccc1OC[C@H]1CC[C@H](N1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=FAIPBAJGPKMFRU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11089   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM11089(5-chloro-2-{[(2R,5S)-5-{[(2S)-2-cyanopyrrolidin-1-...)
Affinity DataKi:  10nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed