BDBM110662 US8614234, 130::US9725433, 130
SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(c3)-c3cc(c[nH]3)C(=O)OCC(O)CO)cc2)c1
InChI Key InChIKey=QHWJRQVVIZMMLO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 110662
Affinity DataIC50: 43nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:The cytoplasmic domain of the human VEGF receptor (VEGFR-2) was expressed as a Histidine-tagged fusion protein following infection of insect cells us...More data for this Ligand-Target Pair