BDBM11048 N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-({2-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)carbamoyl]ethyl}disulfanyl)propanamide::N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]-3-[(3-{[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]amino}-3-oxopropyl)dithio]propanamide::disulfide-containing sulfonamide 3

SMILES NS(=O)(=O)c1nnc(NC(=O)CCSSCCC(=O)Nc2nnc(s2)S(N)(=O)=O)s1

InChI Key InChIKey=ATIAHMMSIUIHRM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11048   

TargetCarbonic anhydrase 9(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11048(N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-({2-[(5-su...)
Affinity DataKi:  18nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11048(N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-({2-[(5-su...)
Affinity DataKi:  60nM ΔG°:  -9.75kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

LigandPNGBDBM11048(N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)-3-({2-[(5-su...)
Affinity DataKi:  61nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed