BDBM11028 1-Acetamido-5-sulfonamidoindane::CHEMBL359768::Indanesulfonamide Derivative 5::N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide

SMILES CC(=O)NC1CCc2cc(ccc12)S(N)(=O)=O

InChI Key InChIKey=RUUYVLNZHGCPRP-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 11028   

TargetCarbonic anhydrase 12(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  0.320nMAssay Description:Inhibition of human carbonic anhydrase 12 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human carbonic anhydrase 7 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Joseph Fourier University

Curated by ChEMBL
LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Joseph Fourier University

Curated by ChEMBL
LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Joseph Fourier University

Curated by ChEMBL
LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  186nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Namur

LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  193nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
University of Namur

Curated by ChEMBL
LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  842nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Joseph Fourier University

Curated by ChEMBL
LigandPNGBDBM11028(N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)acetamide...)
Affinity DataKi:  5.65E+4nM ΔG°:  -5.73kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2006
Entry Details Article
PubMed