BDBM11018 2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-4,6-dione::8-(3-chlorostyryl)caffeine (CSC)

SMILES CC1c2nc(\C=C\c3cccc(Cl)c3)n(C)c2C(=O)N(C)C1=O

InChI Key InChIKey=SGHZGTKRNQIIHB-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 11018   

TargetAmine oxidase [flavin-containing] B(Human)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi:  100nM ΔG°:  -9.54kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Mouse)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi:  200nM ΔG°:  -9.13kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi:  200nM ΔG°:  -9.13kcal/molepH: 7.5 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi:  1.10E+3nM ΔG°:  -8.12kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase(Horse)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi:  1.40E+3nM ΔG°:  -7.98kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B [I199F](Human)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi: >1.00E+6nMAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase(Sheep)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi: >1.00E+6nM ΔG°: >-4.09kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Bovine)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi: >1.00E+6nM ΔG°: >-4.09kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Emory University

LigandPNGBDBM11018(2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-...)
Affinity DataKi: >1.00E+6nM ΔG°: >-4.09kcal/molepH: 7.5 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically. Competitive Ki values for both enzymes were determined by measuring initial rates ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed