BDBM110159 8-Phenoxymethyl-1,3,7-triethylxanthine (8d)

SMILES CCn1c(COc2ccccc2)nc2n(CC)c(=O)n(CC)c(=O)c12

InChI Key InChIKey=ODWDXVCOMQAWIP-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 110159   

TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM110159(8-Phenoxymethyl-1,3,7-triethylxanthine (8d))
Affinity DataKi:  356nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat brain cortical membranes in absence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM110159(8-Phenoxymethyl-1,3,7-triethylxanthine (8d))
Affinity DataKi:  368nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat brain cortical membranes in presence of 0.1 mM GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM110159(8-Phenoxymethyl-1,3,7-triethylxanthine (8d))
Affinity DataKi:  397nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranes in presence of 0.1 mM GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM110159(8-Phenoxymethyl-1,3,7-triethylxanthine (8d))
Affinity DataKi:  416nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranes in absence of GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM110159(8-Phenoxymethyl-1,3,7-triethylxanthine (8d))
Affinity DataKi:  416nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
North-West University, Private Bag X6001, Potchefstroom 2520, South Africa

LigandPNGBDBM110159(8-Phenoxymethyl-1,3,7-triethylxanthine (8d))
Affinity DataKi: >1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
North-West University, Private Bag X6001, Potchefstroom 2520, South Africa

LigandPNGBDBM110159(8-Phenoxymethyl-1,3,7-triethylxanthine (8d))
Affinity DataKi:  2.64E+3nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in Sprague-Dawley rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMed