BDBM110118 US8609678, 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [171]

SMILES COc1cc2CCN(Cc2cc1OC)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=RFKMLYGYWJOZFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110118   

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110118(US8609678, 2-(6,7-dimethoxy-3,4-dihydroisoquinolin...)
Affinity DataIC50: 2nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110118(US8609678, 2-(6,7-dimethoxy-3,4-dihydroisoquinolin...)
Affinity DataIC50: 46nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent