BDBM110038 US8609678, 7-(5-(2,6-dimethylphenylamino)-1-oxoisoindolin-2-yl)-N-hydroxyheptanamide [91]

SMILES Cc1cccc(C)c1Nc1ccc2C(=O)N(CCCCCCC(=O)NO)Cc2c1

InChI Key InChIKey=HTUBQOSBRCOCGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110038   

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110038(US8609678, 7-(5-(2,6-dimethylphenylamino)-1-oxoiso...)
Affinity DataIC50: 3nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM110038(US8609678, 7-(5-(2,6-dimethylphenylamino)-1-oxoiso...)
Affinity DataIC50: 37nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent