BDBM109968 US8609678, 4-((2,6-difluorophenyl)(methyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide [20]::US8609678, 7-(4-((2,6-difluorophenyl)(methyl)amino)benzylamino)-N-hydroxyheptanamide [24]

SMILES CN(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1c(F)cccc1F

InChI Key InChIKey=QYSDDGFAOULDRL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 109968   

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM109968(US8609678, 7-(4-((2,6-difluorophenyl)(methyl)amino...)
Affinity DataIC50: 2nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM109968(US8609678, 7-(4-((2,6-difluorophenyl)(methyl)amino...)
Affinity DataIC50: 121nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM109968(US8609678, 7-(4-((2,6-difluorophenyl)(methyl)amino...)
Affinity DataIC50: 17nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM109968(US8609678, 7-(4-((2,6-difluorophenyl)(methyl)amino...)
Affinity DataIC50: 67nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
Go to US Patent