BDBM109275 US8609622, 2

SMILES COc1ccc(Cc2cc(ccc2Cl)[C@@]23OC[C@@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)c(F)c1F

InChI Key InChIKey=ULTLQRPKEDOYSJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 109275   

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109275(US8609622, 2)
Affinity DataIC50: 1.42nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSGLT1 protein(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109275(US8609622, 2)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109275(US8609622, 2)
Affinity DataIC50: 3.65nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent

TargetSGLT1 protein(Mouse)
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109275(US8609622, 2)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
Go to US Patent