BDBM109231 N-(3-(5-(1-(2-(Benzo[d]thiazol-2-yl)hydrazono)ethyl)furan-2-yl)phenylsulfonyl)-6-phenylhexanamide (Compound 2)

SMILES CC(N=Nc1nc2ccccc2s1)c1ccc(o1)-c1cccc(c1)S(=O)(=O)NC(=O)CCCCCc1ccccc1

InChI Key InChIKey=JIUYDXDVOQKWNU-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109231   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Walter and Eliza Hall Institute of Medical Research

LigandPNGBDBM109231(N-(3-(5-(1-(2-(Benzo[d]thiazol-2-yl)hydrazono)ethy...)
Affinity DataIC50: 770nMpH: 7.4 T: 2°CAssay Description:Each 384-well plate was prepared with 4.75 µL of working assay buffer (50 mM HEPES, 10 mM DTT, 100 mM NaCl, 0.05% Tween029 and 0.1 mg/mL casein,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2014
Entry Details Article
PubMed
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Human)
Walter and Eliza Hall Institute of Medical Research

LigandPNGBDBM109231(N-(3-(5-(1-(2-(Benzo[d]thiazol-2-yl)hydrazono)ethy...)
Affinity DataKd:  230nMpH: 2.2 T: 2°CAssay Description:A concentration series of each compound was injected at a flow rate of 90 µL/min over three spots at 25°C. The times allowed for compound a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2014
Entry Details Article
PubMed