BDBM109032 US10793535, Cmpd ID 614::US8604016, 614::US9938267, Cmpd ID 614

SMILES FC(F)(F)Oc1ccccc1CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1

InChI Key InChIKey=RNBFZCUEZCEVSE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 109032   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM109032(US8604016, 614 | US9938267, Cmpd ID 614 | US107935...)
Affinity DataIC50: 8nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM109032(US8604016, 614 | US9938267, Cmpd ID 614 | US107935...)
Affinity DataIC50: 8nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM109032(US8604016, 614 | US9938267, Cmpd ID 614 | US107935...)
Affinity DataIC50: 8nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent