BDBM108951 US10793535, Cmpd ID 533::US8604016, 533::US9938267, Cmpd ID 533

SMILES Fc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3Cl)nn2)s1

InChI Key InChIKey=VUDXDCSKAVJVDG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 108951   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108951(US8604016, 533 | US9938267, Cmpd ID 533 | US107935...)
Affinity DataIC50: 7nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108951(US8604016, 533 | US9938267, Cmpd ID 533 | US107935...)
Affinity DataIC50: 7nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108951(US8604016, 533 | US9938267, Cmpd ID 533 | US107935...)
Affinity DataIC50: 7nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent