BDBM10883 4,5-dichlorobenzene-1,3-disulfonamide::CHEMBL17::Dichlorophenamide::Dichlorophenamide (DCP)::Dichlorophenamide, DCP::Sulfonamide, 4::US10172837, Dichlorphenamide::sulfonamide 4
SMILES c1c(cc(c(c1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
InChI Key InChIKey=GJQPMPFPNINLKP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 350 hits for monomerid = 10883
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibitory activity of compound against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.19E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human full length carbonic anhydrase 7 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory potency against human cloned Carbonic anhydrase II expressed in Escherichia coli strain BL21More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Sulfurihydrogenibium sp. (strain YO3AOP1))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Inhibition of recombinant Sulfurihydrogenibium yellowstonense YO3AOP1 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of human full length carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 21nM ΔG°: -10.5kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human recombinant CA5B mitochondrial isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of human carbonic anhydrase 5BMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 23nM ΔG°: -10.4kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 13 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibitory activity against murine carbonic anhydrase XIII (mCA XIII) by using CO2 hydrase assay methodMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Ki value against murine carbonic anhydrase XIIIMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of mouse carbonic anhydrase 13More data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universita Degli Studi Di Firenze
Curated by ChEMBL
Universita Degli Studi Di Firenze
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibitory potency against human cloned Carbonic anhydrase I expressed in Escherichia coli strain BL21More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 26nM ΔG°: -10.3kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of human carbonic anhydrase 7More data for this Ligand-Target Pair
Affinity DataKi: 26.5nM ΔG°: -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
Affinity DataKi: 26.5nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibitory potency against catalytic domain of human Carbonic anhydrase IX expressed in Escherichia coli strain BL21More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 38nM ΔG°: -10.0kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 38nM ΔG°: -10.1kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 38nM ΔG°: -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: 38nM ΔG°: -10.1kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human carbonic anhydrase 1-catalyzed CO2 hydration preincubated for 10 mins by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human cloned cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human carbonic anhydrase-2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair