BDBM108804 US8604016, 384::US9938267, Cmpd ID 384

SMILES CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1

InChI Key InChIKey=LMFZBCFZUPGXRB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 108804   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108804(US8604016, 384 | US9938267, Cmpd ID 384)
Affinity DataIC50: 3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108804(US8604016, 384 | US9938267, Cmpd ID 384)
Affinity DataIC50: 81nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108804(US8604016, 384 | US9938267, Cmpd ID 384)
Affinity DataIC50: 81nMAssay Description:No preinc (Column 4).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108804(US8604016, 384 | US9938267, Cmpd ID 384)
Affinity DataIC50: 3nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent