BDBM108739 US10793535, Cmpd ID 318::US8604016, 318::US9938267, Cmpd ID 318

SMILES OC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1)c1cccc(Cl)c1

InChI Key InChIKey=YMVAHDWFRWUEDF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 108739   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108739(US8604016, 318 | US9938267, Cmpd ID 318 | US107935...)
Affinity DataIC50: 6nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108739(US8604016, 318 | US9938267, Cmpd ID 318 | US107935...)
Affinity DataIC50: 180nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108739(US8604016, 318 | US9938267, Cmpd ID 318 | US107935...)
Affinity DataIC50: 180nMAssay Description:No preinc (Column 4).More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108739(US8604016, 318 | US9938267, Cmpd ID 318 | US107935...)
Affinity DataIC50: 6nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
Go to US Patent

TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108739(US8604016, 318 | US9938267, Cmpd ID 318 | US107935...)
Affinity DataIC50: 6nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetGlutamate dehydrogenase 2, mitochondrial(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM108739(US8604016, 318 | US9938267, Cmpd ID 318 | US107935...)
Affinity DataIC50: 180nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent