BDBM108443 US8609688, 21

SMILES Nc1ncccc1-c1nc2ccc(Sc3ccccc3)nc2n1-c1ccc(cc1)C1(N)CCC1

InChI Key InChIKey=HMGHICRZTLETLF-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108443   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM108443(US8609688, 21)
Affinity DataKd:  110nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM108443(US8609688, 21)
Affinity DataKd:  110nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent