BDBM108441 US8609688, 19

SMILES Nc1ncccc1-c1nc2ccc(Nc3ccccc3)nc2n1-c1ccc(cc1)C1(N)CCC1

InChI Key InChIKey=OLTCJMURNYJUTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108441   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM108441(US8609688, 19)
Affinity DataIC50: 3.77nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM108441(US8609688, 19)
Affinity DataIC50: 3.77nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent