BDBM108437 US8609688, 15

SMILES CC(C)C(=O)N1CCN(CC1)c1cccc(c1)-c1ccc2nc(-c3cccnc3N)n(-c3ccc(cc3)C3(N)CCC3)c2n1

InChI Key InChIKey=AWSSGFVYCHJQAJ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108437   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM108437(US8609688, 15)
Affinity DataKd:  1.10nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Arqule

US Patent
LigandPNGBDBM108437(US8609688, 15)
Affinity DataKd:  1.10nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
Go to US Patent