BDBM108417 US8604206, 6

SMILES O[C@@H]1CNC[C@H](C(F)F)[C@H]1O

InChI Key InChIKey=QSMPJEGWIQSKCL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108417   

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandPNGBDBM108417(US8604206, 6)
Affinity DataKi:  3.06nM IC50: 5.80nMpH: 7.0Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent

TargetLysosomal acid glucosylceramidase(Human)
Amicus Therapeutics

US Patent
LigandPNGBDBM108417(US8604206, 6)
Affinity DataKi:  13.6nM IC50: 25.9nMpH: 5.2Assay Description:The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2014
Entry Details
Go to US Patent