BDBM108214 US8598172, 1

SMILES CC[C@H]1N(C2CCCC2)c2nc(Nc3cc(ccc3OC(F)(F)F)N3CCN(C)CC3)ncc2N(C)C1=O

InChI Key InChIKey=UKDYPCZCLRCOMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 108214   

TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM108214(US8598172, 1)
Affinity DataIC50: 32nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM108214(US8598172, 1)
Affinity DataIC50: 1.13E+3nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM108214(US8598172, 1)
Affinity DataIC50: 1.29E+3nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent