BDBM108180 US8598157, I-57

SMILES COCCN1CCN(CC1)c1ncnc(C)c1C#Cc1cnc(C)c(NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=VJFJEDNHGDABKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108180   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM108180(US8598157, I-57)
Affinity DataIC50: 0.830nMT: 2°CAssay Description:This PI3Kalpha assay provides an IC50 value indicative of the activity of the compounds to inhibit PI3 kinase alpha activity. Inhibition of PI3 kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2014
Entry Details
Go to US Patent