BDBM107846 US8598155, 84

SMILES COC(=O)NC1CN(C1)c1ncnn2c(C)nc(-c3cnn(C)c3-c3ccc(C)cc3)c12

InChI Key InChIKey=DXJPYJYUOJVGFN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107846   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Pfizer

US Patent

LigandBDBM107846(US8598155, 84)Copy SMILESCopy InChI

Affinity DataIC50: 4.59nMAssay Description:The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2014
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL