BDBM107777 US8598155, 14

SMILES Cc1nc(-c2cnn(C)c2-c2ccc(cc2)C(F)(F)F)c2c(ncnn12)N1CC(F)(F)C1

InChI Key InChIKey=PBSKSSCHVHEAQF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107777   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Pfizer

US Patent

LigandBDBM107777(US8598155, 14)Copy SMILESCopy InChI

Affinity DataIC50: 1.25nMAssay Description:The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2014
Entry Details
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