BDBM107770 US8598155, 5

SMILES Cc1nc(-c2cnn(C)c2-c2ccc(Cl)cn2)c2c(ncnn12)N1CCC1

InChI Key InChIKey=CSENBHMOZDDBTJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107770   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Pfizer

US Patent

LigandBDBM107770(US8598155, 5)Copy SMILESCopy InChI

Affinity DataIC50: 8.19nMAssay Description:The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2014
Entry Details
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TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Pfizer

US Patent

LigandBDBM107770(US8598155, 5)Copy SMILESCopy InChI

Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human N-terminal FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate after 30 mins by SPAMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/2/2019
Entry Details Article
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