BDBM107758 US8598217, 167

SMILES CN(C)C1CCN(CC1)c1ccc2[nH]c(nc2n1)C(=O)c1ccnc(c1)-c1c(C)n[nH]c1C

InChI Key InChIKey=MGKFAGTZWMNNBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107758   

TargetCyclin-dependent kinase 4(Rabbit)
Astex Therapeutics

US Patent
LigandPNGBDBM107758(US8598217, 167)
Affinity DataIC50: 195nMpH: 7.5Assay Description:A 384-well microtiter Lance TR-FRET (time-resolved-fluorescence energy transfer) endpoint assay was used for CDK4/cyclin D1 kinase activity measureme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2014
Entry Details
Go to US Patent