BDBM107738 CHEMBL2347113::US8933095, 22

SMILES COc1cccc(Cc2nn(C)c3N(O)C(=O)[C@@H](N)Cc23)c1

InChI Key InChIKey=JSPGMJXQPIKTMC-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 107738   

LigandPNGBDBM107738(CHEMBL2347113 | US8933095, 22)
Affinity DataIC50: 65.6nMAssay Description:Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2014
Entry Details
Go to US Patent

LigandPNGBDBM107738(CHEMBL2347113 | US8933095, 22)
Affinity DataIC50: 65.6nMT: 2°CAssay Description:Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent

LigandPNGBDBM107738(CHEMBL2347113 | US8933095, 22)
Affinity DataIC50: 66nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM107738(CHEMBL2347113 | US8933095, 22)
Affinity DataKi:  22nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed