BDBM107691 2,3-dihydroxy-N'-(2-hydroxybenzoyl)benzohydrazide (Compound 17)

SMILES Oc1cccc(C(=O)NNC(=O)c2ccccc2O)c1O

InChI Key InChIKey=DNCBPZLOUZEIIO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 107691   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Nirma University

LigandPNGBDBM107691(2,3-dihydroxy-N'-(2-hydroxybenzoyl)benzohydraz...)
Affinity DataIC50: 500nMAssay Description:HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2014
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM107691(2,3-dihydroxy-N'-(2-hydroxybenzoyl)benzohydraz...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of manganeseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM107691(2,3-dihydroxy-N'-(2-hydroxybenzoyl)benzohydraz...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of manganeseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM107691(2,3-dihydroxy-N'-(2-hydroxybenzoyl)benzohydraz...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM107691(2,3-dihydroxy-N'-(2-hydroxybenzoyl)benzohydraz...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of magnesiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed