BDBM107115 US8592423, 5,7-Dimethyl-2-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)cyclopropyl)-[1,2,4]-triazolo[1,5-a]pyrimidine

SMILES Cc1cc(C)n2nc(nc2n1)C1CC1c1nc(cn1C)-c1ccccc1

InChI Key InChIKey=RDDGPEGWTDILLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107115   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM107115(US8592423, 5,7-Dimethyl-2-(2-(1-methyl-4-phenyl-1H...)
Affinity DataIC50: 14.5nMAssay Description:PDE10 activity was measured using Scintillation Proximity Assay (SPA)-based methods. PDE10 catalyses the hydrolysis of the intracellular messenger ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2014
Entry Details
Go to US Patent