BDBM10704 3-{[methyl(7-{[(2E)-1-oxo-2-(3,4,5-trimethoxybenzylidene)-2,3-dihydro-1H-inden-5-yl]oxy}heptyl)amino]methyl}phenyl methylcarbamate::Xanthostigmine deriv. 20

SMILES CNC(=O)Oc1cccc(CN(C)CCCCCCCOc2ccc3C(=O)C(Cc3c2)=Cc2cc(OC)c(OC)c(OC)c2)c1

InChI Key InChIKey=KYVIWBPYFDCUME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10704   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10704(3-{[methyl(7-{[(2E)-1-oxo-2-(3,4,5-trimethoxybenzy...)
Affinity DataIC50: 1.80nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10704(3-{[methyl(7-{[(2E)-1-oxo-2-(3,4,5-trimethoxybenzy...)
Affinity DataIC50: 81.3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2006
Entry Details Article
PubMed