BDBM107003 CHEMBL575447::US8592579, 110

SMILES C[C@]1(CCCN1c1nc(Nc2cc([nH]n2)C2CC2)c2cccn2n1)C(=O)Nc1cnccn1

InChI Key InChIKey=YSRFTZRNFJRVPH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 107003   

TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM107003(CHEMBL575447 | US8592579, 110)
Affinity DataIC50: 2nMpH: 7.4Assay Description:Kinase assay using IGF1-receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM107003(CHEMBL575447 | US8592579, 110)
Affinity DataIC50: 3nMAssay Description:Inhibition of IGF1R after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
LigandPNGBDBM107003(CHEMBL575447 | US8592579, 110)
Affinity DataIC50: 897nMAssay Description:Inhibition of CDK2/Cyclin E after 60 mins by fluorescence electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed