BDBM106964 US8592581, 15

SMILES CC(C)n1cnc2c(NCc3cccnc3)nc(NCC(O)C(F)(F)F)nc12

InChI Key InChIKey=XQYCTMGXRKRCSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106964   

TargetCyclin-dependent kinase 2(Human)
Cyclacel

US Patent
LigandPNGBDBM106964(US8592581, 15)
Affinity DataIC50: 570nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 9(Human)
Cyclacel

US Patent
LigandPNGBDBM106964(US8592581, 15)
Affinity DataIC50: 7.40E+3nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent