BDBM106951 US8592581, 2

SMILES CC[C@H](Nc1nc(NCc2ccc(C)nc2)c2ncn(C(C)C)c2n1)[C@@H](C)O

InChI Key InChIKey=PUWYYRSVRUBXLF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 106951   

TargetCyclin-dependent kinase 2(Human)
Cyclacel

US Patent
LigandPNGBDBM106951(US8592581, 2)
Affinity DataIC50: 520nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Cyclacel

US Patent
LigandPNGBDBM106951(US8592581, 2)
Affinity DataIC50: 3.25E+3nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Cyclacel

US Patent
LigandPNGBDBM106951(US8592581, 2)
Affinity DataIC50: 3.63E+3nMpH: 7.5 T: 2°CAssay Description:To evaluate the in-vitro kinase potency of the compounds, they were screened against CDK 2 and CDK9. Kinase assays were performed in 96-well plates u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
US Patent