BDBM106944 US8592468, EbSe2

SMILES O=c1[nH][se]c2ccccc12

InChI Key InChIKey=UELHWVKBVJWUPY-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106944   

TargetMicrotubule-associated protein 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM106944(US8592468, EbSe2)
Affinity DataIC50: 4.97E+3nMAssay Description:Non-covalent/mixed type inhibition of recombinant human MetAP2 using Met-AMC as substrate preincubated for 30 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM106944(US8592468, EbSe2)
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM106944(US8592468, EbSe2)
Affinity DataIC50: 6.92E+3nMAssay Description:Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM106944(US8592468, EbSe2)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetThioredoxin reductase(Escherichia coli (strain K12))
Thioredoxin Systems

US Patent
LigandPNGBDBM106944(US8592468, EbSe2)
Affinity DataKi:  1.00E+3nM IC50: 1.50E+4nMAssay Description:All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2H)-one derivatives were tested as potential E. coli TrxR inhibitors by standard DTNB as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2014
Entry Details
Go to US Patent