BDBM10690 (-)-N8-benzylnorphysostigmine::(3aS)-1-benzyl-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate::CHEMBL76241

SMILES CNC(=O)Oc1ccc2N(C)C3N(Cc4ccccc4)CC[C@@]3(C)c2c1

InChI Key InChIKey=GVJXSDRIRBRKBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10690   

TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10690((3aS)-1-benzyl-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 10.4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10690((3aS)-1-benzyl-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 330nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Niddk

Curated by ChEMBL
LigandPNGBDBM10690((3aS)-1-benzyl-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 990nMAssay Description:In vitro inhibitory activity against acetylcholinesterase from electric eelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed