BDBM106595 CHEMBL2206380::US8586617, 62

SMILES CC(C)N(Cc1cnc[nH]1)c1ccc(F)cc1

InChI Key InChIKey=VRTRCQWZSDTCHC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106595   

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM106595(CHEMBL2206380 | US8586617, 62)
Affinity DataKi:  8.10nM ΔG°:  -10.3kcal/moleT: 2°CAssay Description:Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106595(CHEMBL2206380 | US8586617, 62)
Affinity DataKi:  13nMAssay Description:Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed