BDBM106574 CHEMBL2206404::US8586617, 7

SMILES CC(C)N(Cc1cnc[nH]1)c1ccccc1

InChI Key InChIKey=ZJORNDARWIBRJD-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106574   

TargetTrace amine-associated receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106574(CHEMBL2206404 | US8586617, 7)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at human TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106574(CHEMBL2206404 | US8586617, 7)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at rat TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106574(CHEMBL2206404 | US8586617, 7)
Affinity DataEC50:  28nMAssay Description:Agonist activity at mouse TAAR1 receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106574(CHEMBL2206404 | US8586617, 7)
Affinity DataKi:  4.60nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent

TargetTrace amine-associated receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM106574(CHEMBL2206404 | US8586617, 7)
Affinity DataKi:  22nMAssay Description:Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed