BDBM106559 US8586600, II-54

SMILES CC(Cl)C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key InChIKey=WKTBMWCHAMDMIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106559   

TargetPlatelet-derived growth factor receptor alpha(Human)
Celgene Avilomics Research

US Patent
LigandPNGBDBM106559(US8586600, II-54)
Affinity DataIC50: 185nMAssay Description:Compounds may also be assayed as inhibitors of PDGFR in a manner substantially similar to the method described in Roberts, et al., “Antiangiogen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
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TargetMast/stem cell growth factor receptor Kit(Human)
Celgene Avilomics Research

US Patent
LigandPNGBDBM106559(US8586600, II-54)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2014
Entry Details
Go to US Patent