BDBM106381 N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6-yl]-amides (12)

SMILES [O-][N+](=O)c1ccc(cc1)C(=O)Nc1nc(nc2n(Cc3ccccc3F)nnc12)-c1ccccc1

InChI Key InChIKey=WEAIIEYARJCNTR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106381   

TargetAdenosine receptor A2a(Human)
University of Pisa

LigandPNGBDBM106381(N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6...)
Affinity DataKi:  14nMpH: 7.4Assay Description:For A1 adenosine receptors, 40 mg of protein were incubated for 60 min at 25°C with [3H]DPCPX 0.5 nM (Kd = 0.4 nM) and increasing concentrations...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2014
Entry Details Article
PubMed