BDBM106152 US9695172, 2-221

SMILES CN1c2ccccc2C(=O)N(C)c2ccc(Nc3ccc(cc3)S(N)(=O)=O)nc12

InChI Key InChIKey=RCVIFGTXCWQDHC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106152   

TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 2.99E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent

TargetBromodomain testis-specific protein(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 5.66E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent

TargetAurora kinase A(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent

TargetAurora kinase B(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent

TargetAurora kinase C(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM106152(US9695172, 2-221)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
Go to US Patent